Adding Selectivity to Antimicrobial Peptides: Rational Design of a Multidomain Peptide against Pseudomonas spp.

Currently available antimicrobials exhibit broad killing with regard to bacterial genera and species. Indiscriminate killing of microbes by these conventional antibiotics can disrupt the ecological balance of the indigenous microbial flora, often resulting in negative clinical consequences. Species-...

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Hlavní autoři: Eckert, Randal, Qi, Fengxia, Yarbrough, Daniel K., He, Jian, Anderson, Maxwell H., Shi, Wenyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
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Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426969/
https://ncbi.nlm.nih.gov/pubmed/16569868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1480-1488.2006
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