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Hypomethylation of TET2 Target Genes Identifies a Curable Subset of Acute Myeloid Leukemia
BACKGROUND: Acute myeloid leukemia (AML) is curable in a subset of cases. The DNA methylation regulator TET2 is frequently mutated in AML, and we hypothesized that studying TET2-specific differentially methylated CpGs (tet2-DMCs) improves AML classification. METHODS: We used bisulfite pyrosequencing...
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| Gepubliceerd in: | J Natl Cancer Inst |
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| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862435/ https://ncbi.nlm.nih.gov/pubmed/26568194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv323 |
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