A comprehensive survey of the mutagenic impact of common cancer cytotoxics

BACKGROUND: Genomic mutations caused by cytotoxic agents used in cancer chemotherapy may cause secondary malignancies as well as contribute to the evolution of treatment-resistant tumour cells. The stable diploid genome of the chicken DT40 lymphoblast cell line, an established DNA repair model syste...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Szikriszt, Bernadett, Póti, Ádám, Pipek, Orsolya, Krzystanek, Marcin, Kanu, Nnennaya, Molnár, János, Ribli, Dezső, Szeltner, Zoltán, Tusnády, Gábor E., Csabai, István, Szallasi, Zoltan, Swanton, Charles, Szüts, Dávid
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862131/
https://ncbi.nlm.nih.gov/pubmed/27161042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0963-7
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