Negative modulation of α5 GABAA receptors in rats may partially prevent memory impairment induced by MK-801, but not amphetamine- or MK-801-elicited hyperlocomotion

Reportedly, negative modulation of α(5) GABA(A) receptors may improve cognition in normal and pharmacologically-impaired animals, and such modulation has been proposed as an avenue for treatment of cognitive symptoms in schizophrenia. This study assessed the actions of PWZ-029, administered at doses...

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Detalhes bibliográficos
Publicado no:J Psychopharmacol
Main Authors: Stamenić, Tamara Timić, Joksimović, Srdjan, Biawat, Poonam, Stanković, Tamara, Marković, Bojan, Cook, James M, Savić, Miroslav M
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861997/
https://ncbi.nlm.nih.gov/pubmed/26105958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881115590601
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