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SH-I-048A, AN IN VITRO NONSELECTIVE SUPER-AGONIST AT THE BENZODIAZEPINE SITE OF GABAA RECEPTORS: THE APPROXIMATED ACTIVATION OF RECEPTOR SUBTYPES MAY EXPLAIN BEHAVIORAL EFFECTS

Enormous progress in understanding the role of four populations of benzodiazepine-sensitive GABA(A) receptors was paralleled by the puzzling findings suggesting that substantial separation of behavioral effects may be accomplished by apparently non-selective modulators. We report on SH-I-048A, a new...

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Detalhes bibliográficos
Main Authors: Obradović, Aleksandar Lj., Joksimović, Srđan, Poe, Michael M., Ramerstorfer, Joachim, Varagic, Zdravko, Namjoshi, Ojas, Batinić, Bojan, Radulović, Tamara, Marković, Bojan, Roth, Brian, Sieghart, Werner, Cook, James M., Savić, Miroslav M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996760/
https://ncbi.nlm.nih.gov/pubmed/24472579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.01.036
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