Hot spots of DNA double-strand breaks in human rDNA units are produced in vivo

Endogenous hot spots of DNA double-strand breaks (DSBs) are tightly linked with transcription patterns and cancer genomics(1,2). There are nine hot spots of DSBs located in human rDNA units(3–6). Here we describe that the profiles of these hot spots coincide with the profiles of γ-H2AX or H2AX, stro...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Tchurikov, Nickolai A., Yudkin, Dmitry V., Gorbacheva, Maria A., Kulemzina, Anastasia I., Grischenko, Irina V., Fedoseeva, Daria M., Sosin, Dmitri V., Kravatsky, Yuri V., Kretova, Olga V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861929/
https://ncbi.nlm.nih.gov/pubmed/27160357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25866
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