Hot spots of DNA double-strand breaks and genomic contacts of human rDNA units are involved in epigenetic regulation

DNA double-strand breaks (DSBs) are involved in many cellular mechanisms, including replication, transcription, and genome rearrangements. The recent observation that hot spots of DSBs in human chromosomes delimit DNA domains that possess coordinately expressed genes suggests a strong relationship b...

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Publicat a:J Mol Cell Biol
Autors principals: Tchurikov, Nickolai A., Fedoseeva, Daria M., Sosin, Dmitri V., Snezhkina, Anastasia V., Melnikova, Nataliya V., Kudryavtseva, Anna V., Kravatsky, Yuri V., Kretova, Olga V.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524424/
https://ncbi.nlm.nih.gov/pubmed/25280477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mju038
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