Hot spots of DNA double-strand breaks and genomic contacts of human rDNA units are involved in epigenetic regulation

DNA double-strand breaks (DSBs) are involved in many cellular mechanisms, including replication, transcription, and genome rearrangements. The recent observation that hot spots of DSBs in human chromosomes delimit DNA domains that possess coordinately expressed genes suggests a strong relationship b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Cell Biol
Prif Awduron: Tchurikov, Nickolai A., Fedoseeva, Daria M., Sosin, Dmitri V., Snezhkina, Anastasia V., Melnikova, Nataliya V., Kudryavtseva, Anna V., Kravatsky, Yuri V., Kretova, Olga V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524424/
https://ncbi.nlm.nih.gov/pubmed/25280477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mju038
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