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Small-Molecule Binding Aptamers: Selection Strategies, Characterization, and Applications
Aptamers are single-stranded, synthetic oligonucleotides that fold into 3-dimensional shapes capable of binding non-covalently with high affinity and specificity to a target molecule. They are generated via an in vitro process known as the Systematic Evolution of Ligands by EXponential enrichment, f...
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| Veröffentlicht in: | Front Chem |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861895/ https://ncbi.nlm.nih.gov/pubmed/27242994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2016.00014 |
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