IL-19 Halts Progression of Atherosclerotic Plaque, Polarizes, and Increases Cholesterol Uptake and Efflux in Macrophages

Atherosclerosis regression is an important clinical goal, and treatments that can reverse atherosclerotic plaque formation are actively being sought. Our aim was to determine whether administration of exogenous IL-19, a Th2 cytokine, could attenuate progression of preformed atherosclerotic plaque an...

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Udgivet i:Am J Pathol
Main Authors: Gabunia, Khatuna, Ellison, Stephen, Kelemen, Sheri, Kako, Farah, Cornwell, William D., Rogers, Thomas J., Datta, Prasun K., Ouimet, Mireille, Moore, Kathryn J., Autieri, Michael V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2016
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861768/
https://ncbi.nlm.nih.gov/pubmed/26952642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.12.023
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