IL-19 Halts Progression of Atherosclerotic Plaque, Polarizes, and Increases Cholesterol Uptake and Efflux in Macrophages

Atherosclerosis regression is an important clinical goal, and treatments that can reverse atherosclerotic plaque formation are actively being sought. Our aim was to determine whether administration of exogenous IL-19, a Th2 cytokine, could attenuate progression of preformed atherosclerotic plaque an...

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Bibliographic Details
Published in:Am J Pathol
Main Authors: Gabunia, Khatuna, Ellison, Stephen, Kelemen, Sheri, Kako, Farah, Cornwell, William D., Rogers, Thomas J., Datta, Prasun K., Ouimet, Mireille, Moore, Kathryn J., Autieri, Michael V.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2016
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861768/
https://ncbi.nlm.nih.gov/pubmed/26952642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.12.023
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