Mutation of Serine 32 to Threonine in Peroxiredoxin 6 Preserves Its Structure and Enzymatic Function but Abolishes Its Trafficking to Lamellar Bodies

Peroxiredoxin 6 (Prdx6), a bifunctional protein with phospholipase A(2) (aiPLA(2)) and GSH peroxidase activities, protects lungs from oxidative stress and participates in lung surfactant phospholipid turnover. Prdx6 has been localized to both cytosol and lamellar bodies (LB) in lung epithelium, and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sorokina, Elena M., Dodia, Chandra, Zhou, Suiping, Tao, Jian-Qin, Gao, Ling, Raabe, Tobias, Feinstein, Sheldon I., Fisher, Aron B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861491/
https://ncbi.nlm.nih.gov/pubmed/26921317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.698894
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados