Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gα(o) and R7-binding Protein

RGS (regulator of G protein signaling) proteins of the R7 subfamily (RGS6, -7, -9, and -11) are highly expressed in neurons where they regulate many physiological processes. R7 RGS proteins contain several distinct domains and form obligatory dimers with the atypical Gβ subunit, Gβ(5). They also int...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Tayou, Junior, Wang, Qiang, Jang, Geeng-Fu, Pronin, Alexey N., Orlandi, Cesare, Martemyanov, Kirill A., Crabb, John W., Slepak, Vladlen Z.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861480/
https://ncbi.nlm.nih.gov/pubmed/26895961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.694075
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