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The Different Conformational States of Tissue Transglutaminase Have Opposing Affects on Cell Viability
Tissue transglutaminase (tTG) is an acyltransferase/GTP-binding protein that contributes to the development of various diseases. In human cancer cells, tTG activates signaling pathways that promote cell growth and survival, whereas in other disorders (i.e. neurodegeneration), overexpression of tTG e...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861479/ https://ncbi.nlm.nih.gov/pubmed/26893378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.699108 |
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