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Regulation of Piezo2 Mechanotransduction by Static Plasma Membrane Tension in Primary Afferent Neurons

The Piezo2 channel is a newly identified mammalian mechanical transducer that confers rapidly adapting mechanically activated (RA-MA) currents in primary afferent neurons. The Piezo2 channels sense rapid membrane displacement, but it is not clear whether they are sensitive to osmotic swelling, which...

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Vydáno v:J Biol Chem
Hlavní autoři: Jia, Zhanfeng, Ikeda, Ryo, Ling, Jennifer, Viatchenko-Karpinski, Viacheslav, Gu, Jianguo G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861477/
https://ncbi.nlm.nih.gov/pubmed/26929410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.692384
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