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Regulation of Piezo2 Mechanotransduction by Static Plasma Membrane Tension in Primary Afferent Neurons

The Piezo2 channel is a newly identified mammalian mechanical transducer that confers rapidly adapting mechanically activated (RA-MA) currents in primary afferent neurons. The Piezo2 channels sense rapid membrane displacement, but it is not clear whether they are sensitive to osmotic swelling, which...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jia, Zhanfeng, Ikeda, Ryo, Ling, Jennifer, Viatchenko-Karpinski, Viacheslav, Gu, Jianguo G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861477/
https://ncbi.nlm.nih.gov/pubmed/26929410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.692384
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