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Characterization of temperature-sensitive leak K(+) currents and expression of TRAAK, TREK-1, and TREK2 channels in dorsal root ganglion neurons of rats

Leak K(+) currents are mediated by two-pore domain K(+) (K2P) channels and are involved in controlling neuronal excitability. Of 15 members of K2P channels cloned so far, TRAAK, TREK-1, and TREK-2 are temperature sensitive. In the present study, we show that strong immunoreactivity of TRAAK, TREK-1...

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Vydáno v:Mol Brain
Hlavní autoři: Viatchenko-Karpinski, Viacheslav, Ling, Jennifer, Gu, Jianguo G.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035395/
https://ncbi.nlm.nih.gov/pubmed/29980241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-018-0384-5
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