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The β-Arrestins: Multifunctional Regulators of G Protein-coupled Receptors

The β-arrestins (βarrs) are versatile, multifunctional adapter proteins that are best known for their ability to desensitize G protein-coupled receptors (GPCRs), but also regulate a diverse array of cellular functions. To signal in such a complex fashion, βarrs adopt multiple conformations and are r...

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Pubblicato in:J Biol Chem
Autori principali: Smith, Jeffrey S., Rajagopal, Sudarshan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861465/
https://ncbi.nlm.nih.gov/pubmed/26984408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.713313
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