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Inhibition of Interleukin 1β (IL-1β) Expression by Anthrax Lethal Toxin (LeTx) Is Reversed by Histone Deacetylase 8 (HDAC8) Inhibition in Murine Macrophages

Many pathogenic microbes often release toxins that subvert the host's immune responses to render the environment suitable for their survival and proliferation. LeTx is one of the toxins causing immune paralysis by cleaving and inactivating the mitogen-activated protein kinase (MAPK) kinases (ME...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Ha, Soon-Duck, Reid, Chantelle, Meshkibaf, Shahab, Kim, Sung Ouk
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861443/
https://ncbi.nlm.nih.gov/pubmed/26912657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695809
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