The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility

Cone photoreceptor cyclic nucleotide-gated (CNG) channels play a pivotal role in cone phototransduction, which is a process essential for daylight vision, color vision, and visual acuity. Mutations in the cone channel subunits CNGA3 and CNGB3 are associated with human cone diseases, including achrom...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Ding, Xi-Qin, Thapa, Arjun, Ma, Hongwei, Xu, Jianhua, Elliott, Michael H., Rodgers, Karla K., Smith, Marci L., Wang, Jin-Shan, Pittler, Steven J., Kefalov, Vladimir J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Membrane Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861441/
https://ncbi.nlm.nih.gov/pubmed/26893377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.696138
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