Alternative Splicing Governs Cone Cyclic Nucleotide-gated (CNG) Channel Sensitivity to Regulation by Phosphoinositides

Precursor mRNA encoding CNGA3 subunits of cone photoreceptor cyclic nucleotide-gated (CNG) channels undergoes alternative splicing, generating isoforms differing in the N-terminal cytoplasmic region of the protein. In humans, four variants arise from alternative splicing, but the functional signific...

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Hlavní autoři: Dai, Gucan, Sherpa, Tshering, Varnum, Michael D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Membrane Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036372/
https://ncbi.nlm.nih.gov/pubmed/24675082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.562272
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