Intracellular pH Modulates Autophagy and Mitophagy

The specific autophagic elimination of mitochondria (mitophagy) plays the role of quality control for this organelle. Deregulation of mitophagy leads to an increased number of damaged mitochondria and triggers cell death. The deterioration of mitophagy has been hypothesized to underlie the pathogene...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Berezhnov, Alexey V., Soutar, Marc P. M., Fedotova, Evgeniya I., Frolova, Maria S., Plun-Favreau, Helene, Zinchenko, Valery P., Abramov, Andrey Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861439/
https://ncbi.nlm.nih.gov/pubmed/26893374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691774
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