Intracellular pH Modulates Autophagy and Mitophagy

The specific autophagic elimination of mitochondria (mitophagy) plays the role of quality control for this organelle. Deregulation of mitophagy leads to an increased number of damaged mitochondria and triggers cell death. The deterioration of mitophagy has been hypothesized to underlie the pathogene...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Berezhnov, Alexey V., Soutar, Marc P. M., Fedotova, Evgeniya I., Frolova, Maria S., Plun-Favreau, Helene, Zinchenko, Valery P., Abramov, Andrey Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861439/
https://ncbi.nlm.nih.gov/pubmed/26893374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691774
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