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Intracellular pH Modulates Autophagy and Mitophagy

The specific autophagic elimination of mitochondria (mitophagy) plays the role of quality control for this organelle. Deregulation of mitophagy leads to an increased number of damaged mitochondria and triggers cell death. The deterioration of mitophagy has been hypothesized to underlie the pathogene...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Berezhnov, Alexey V., Soutar, Marc P. M., Fedotova, Evgeniya I., Frolova, Maria S., Plun-Favreau, Helene, Zinchenko, Valery P., Abramov, Andrey Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861439/
https://ncbi.nlm.nih.gov/pubmed/26893374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691774
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