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Intracellular pH Modulates Autophagy and Mitophagy
The specific autophagic elimination of mitochondria (mitophagy) plays the role of quality control for this organelle. Deregulation of mitophagy leads to an increased number of damaged mitochondria and triggers cell death. The deterioration of mitophagy has been hypothesized to underlie the pathogene...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861439/ https://ncbi.nlm.nih.gov/pubmed/26893374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691774 |
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