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Nerve growth factor alters microtubule targeting agent-induced neurotransmitter release but not MTA-induced neurite retraction in sensory neurons

Peripheral neuropathy is a dose-limiting side effect of anticancer treatment with the microtubule-targeted agents (MTAs), paclitaxel and epothilone B (EpoB); however, the mechanisms by which the MTAs alter neuronal function and morphology are unknown. We previously demonstrated that paclitaxel alter...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: PITTMAN, SHERRY K., GRACIAS, NEILIA G., FEHRENBACHER, JILL C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861399/
https://ncbi.nlm.nih.gov/pubmed/26883566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.02.010
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