Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction

BACKGROUND: Assembly and disassembly of microtubules (MTs) is critical for neurite outgrowth and differentiation. Evidence suggests that nerve growth factor (NGF) induces neurite outgrowth from PC12 cells by activating the receptor tyrosine kinase, TrkA. G protein-coupled receptors (GPCRs) as well a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Neurosci
Prif Awduron: Sierra-Fonseca, Jorge A, Najera, Omar, Martinez-Jurado, Jessica, Walker, Ellen M, Varela-Ramirez, Armando, Khan, Arshad M, Miranda, Manuel, Lamango, Nazarius S, Roychowdhury, Sukla
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302597/
https://ncbi.nlm.nih.gov/pubmed/25552352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-014-0132-4
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