Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction

BACKGROUND: Assembly and disassembly of microtubules (MTs) is critical for neurite outgrowth and differentiation. Evidence suggests that nerve growth factor (NGF) induces neurite outgrowth from PC12 cells by activating the receptor tyrosine kinase, TrkA. G protein-coupled receptors (GPCRs) as well a...

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Detalles Bibliográficos
Publicado en:BMC Neurosci
Main Authors: Sierra-Fonseca, Jorge A, Najera, Omar, Martinez-Jurado, Jessica, Walker, Ellen M, Varela-Ramirez, Armando, Khan, Arshad M, Miranda, Manuel, Lamango, Nazarius S, Roychowdhury, Sukla
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302597/
https://ncbi.nlm.nih.gov/pubmed/25552352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-014-0132-4
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