Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction

BACKGROUND: Assembly and disassembly of microtubules (MTs) is critical for neurite outgrowth and differentiation. Evidence suggests that nerve growth factor (NGF) induces neurite outgrowth from PC12 cells by activating the receptor tyrosine kinase, TrkA. G protein-coupled receptors (GPCRs) as well a...

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Publicat a:BMC Neurosci
Autors principals: Sierra-Fonseca, Jorge A, Najera, Omar, Martinez-Jurado, Jessica, Walker, Ellen M, Varela-Ramirez, Armando, Khan, Arshad M, Miranda, Manuel, Lamango, Nazarius S, Roychowdhury, Sukla
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302597/
https://ncbi.nlm.nih.gov/pubmed/25552352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-014-0132-4
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