Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction

BACKGROUND: Assembly and disassembly of microtubules (MTs) is critical for neurite outgrowth and differentiation. Evidence suggests that nerve growth factor (NGF) induces neurite outgrowth from PC12 cells by activating the receptor tyrosine kinase, TrkA. G protein-coupled receptors (GPCRs) as well a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Neurosci
Main Authors: Sierra-Fonseca, Jorge A, Najera, Omar, Martinez-Jurado, Jessica, Walker, Ellen M, Varela-Ramirez, Armando, Khan, Arshad M, Miranda, Manuel, Lamango, Nazarius S, Roychowdhury, Sukla
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302597/
https://ncbi.nlm.nih.gov/pubmed/25552352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-014-0132-4
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