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Lithium ion inhibits nerve growth factor-induced neurite outgrowth and phosphorylation of nerve growth factor-modulated microtubule-associated proteins

LiCl (2.5-20 mM) reversibly suppressed nerve growth factor (NGF)- induced neurite outgrowth by cultured rat PC 12 pheochromocytoma cells. Similar concentrations of LiCl also reversibly blocked NGF-dependent regeneration of neurites by PC12 cells that had been primed by long- term pre-exposure to NGF...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1985
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2113733/
https://ncbi.nlm.nih.gov/pubmed/4030895
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