Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy

Arrhythmogenic cardiomyopathy (ACM) is characterized by redistribution of junctional proteins, arrhythmias, and progressive myocardial injury. We previously reported that SB216763 (SB2), annotated as a GSK3β inhibitor, reverses disease phenotypes in a zebrafish model of ACM. Here, we show that SB2 p...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Chelko, Stephen P., Asimaki, Angeliki, Andersen, Peter, Bedja, Djahida, Amat-Alarcon, Nuria, DeMazumder, Deeptankar, Jasti, Ravirasmi, MacRae, Calum A., Leber, Remo, Kleber, Andre G., Saffitz, Jeffrey E., Judge, Daniel P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861310/
https://ncbi.nlm.nih.gov/pubmed/27170944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85923
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