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Apolipoprotein A-I coating of protamine–oligonucleotide nanoparticles increases particle uptake and transcytosis in an in vitro model of the blood–brain barrier

Drug delivery to the brain is severely restricted by formation of tight junctions between adjacent brain capillary endothelial cells (BCEC). In the present study we have evaluated the effects of protamine–oligonucleotide nanoparticles (proticles) on the functional properties of primary porcine BCEC...

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Bibliografische gegevens
Gepubliceerd in:J Control Release
Hoofdauteurs: Kratzer, Ingrid, Wernig, Karin, Panzenboeck, Ute, Bernhart, Eva, Reicher, Helga, Wronski, Robert, Windisch, Manfred, Hammer, Astrid, Malle, Ernst, Zimmer, Andreas, Sattler, Wolfgang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861216/
https://ncbi.nlm.nih.gov/pubmed/17239472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2006.11.020
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