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Direct Interaction between TalinB and Rap1 is necessary for adhesion of Dictyostelium cells

BACKGROUND: The small G-protein Rap1 is an important regulator of cellular adhesion in Dictyostelium, however so far the downstream signalling pathways for cell adhesion are not completely characterized. In mammalian cells talin is crucial for adhesion and Rap1 was shown to be a key regulator of tal...

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Pubblicato in:BMC Cell Biol
Autori principali: Plak, Katarzyna, Pots, Henderikus, Van Haastert, Peter J. M., Kortholt, Arjan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861126/
https://ncbi.nlm.nih.gov/pubmed/26744136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-015-0078-0
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