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Regulation of Cell Death by IAPs and their Antagonists
Inhibitors of Apoptosis (IAP) family of genes encode BIR domain containing proteins with anti-apoptotic function. These proteins also contain RING or UBC domains and act by binding to major pro-apoptotic factors and ubiquitylating them. High levels of IAPs inhibit caspase-mediated apoptosis. For the...
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| Опубликовано в: : | Curr Top Dev Biol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861076/ https://ncbi.nlm.nih.gov/pubmed/26431568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.ctdb.2015.07.026 |
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