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Two distinct nodes of translational inhibition in the Integrated Stress Response
The Integrated Stress Response (ISR) refers to a signaling pathway initiated by stress-activated eIF2α kinases. Once activated, the pathway causes attenuation of global mRNA translation while also paradoxically inducing stress response gene expression. A detailed analysis of this pathway has helped...
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| Publicado no: | BMB Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korean Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5720466/ https://ncbi.nlm.nih.gov/pubmed/28803610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.11.157 |
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