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Conserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signaling
The highly conserved target of rapamycin complex 1 (TORC1) is the central component of a signaling network that couples a vast range of internal and external stimuli to cell growth, proliferation and metabolism. TORC1 deregulation is associated with a number of human pathologies, including many canc...
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| Pubblicato in: | Cell Discov |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860963/ https://ncbi.nlm.nih.gov/pubmed/27462445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.49 |
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