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SEACing the GAP that nEGOCiates TORC1 activation: Evolutionary conservation of Rag GTPase regulation

The target of rapamycin complex 1 (TORC1) regulates eukaryotic cell growth in response to a variety of input signals. In S. cerevisiae, amino acids activate TORC1 through the Rag guanosine triphosphatase (GTPase) heterodimer composed of Gtr1 and Gtr2 found together with Ego1 and Ego3 in the EGO comp...

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Detalhes bibliográficos
Main Authors: Panchaud, Nicolas, Péli-Gulli, Marie-Pierre, De Virgilio, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875668/
https://ncbi.nlm.nih.gov/pubmed/23974112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26000
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