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SEACing the GAP that nEGOCiates TORC1 activation: Evolutionary conservation of Rag GTPase regulation
The target of rapamycin complex 1 (TORC1) regulates eukaryotic cell growth in response to a variety of input signals. In S. cerevisiae, amino acids activate TORC1 through the Rag guanosine triphosphatase (GTPase) heterodimer composed of Gtr1 and Gtr2 found together with Ego1 and Ego3 in the EGO comp...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3875668/ https://ncbi.nlm.nih.gov/pubmed/23974112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26000 |
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