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Autologous iPSC-derived dopamine neuron transplantation in a nonhuman primate Parkinson’s disease model

Autologous dopamine (DA) neurons are a new cell source for replacement therapy of Parkinson’s disease (PD). In this study, we tested the safety and efficacy of autologous induced pluripotent stem cell (iPSC)-derived DA cells for treatment of a cynomolgus monkey PD model. Monkey bone marrow mesenchym...

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Detalles Bibliográficos
Publicado en:Cell Discov
Main Authors: Wang, Shuyan, Zou, Chunlin, Fu, Linlin, Wang, Bin, An, Jing, Song, Gongru, Wu, Jianyu, Tang, Xihe, Li, Mo, Zhang, Jian, Yue, Feng, Zheng, Chengyun, Chan, Piu, Zhang, Y Alex, Chen, Zhiguo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860772/
https://ncbi.nlm.nih.gov/pubmed/27462412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.12
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