Autologous iPSC-based Vaccines Elicit Anti-Tumor Responses in Vivo

Cancer cells and embryonic tissues share a number of cellular and molecular properties, suggesting that induced pluripotent stem cells (iPSCs) may be harnessed to elicit anti-tumor responses in cancer vaccines. RNA-sequencing revealed that human and murine iPSCs express tumor-associated antigens, an...

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Publicado en:Cell Stem Cell
Autores principales: Kooreman, Nigel G., Kim, Youngkyun, de Almeida, Patricia E., Termglinchan, Vittavat, Diecke, Sebastian, Shao, Ning-Yi, Wei, Tzu-Tang, Yi, Hyoju, Dey, Devaveena, Nelakanti, Raman, Brouwer, Thomas P., Paik, David T., Barfi, Idit, Han, Arnold, Quax, Paul H.A., Hamming, Jaap F., Levy, Ronald, Davis, Mark M., Wu, Joseph C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134179/
https://ncbi.nlm.nih.gov/pubmed/29456158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.01.016
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