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The Evolution of COP9 Signalosome in Unicellular and Multicellular Organisms

The COP9 signalosome (CSN) is a highly conserved protein complex, recently being crystallized for human. In mammals and plants the COP9 complex consists of nine subunits, CSN 1–8 and CSNAP. The CSN regulates the activity of culling ring E3 ubiquitin and plays central roles in pleiotropy, cell cycle,...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Barth, Emanuel, Hübler, Ron, Baniahmad, Aria, Marz, Manja
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860701/
https://ncbi.nlm.nih.gov/pubmed/27044515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evw073
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