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The Evolution of COP9 Signalosome in Unicellular and Multicellular Organisms

The COP9 signalosome (CSN) is a highly conserved protein complex, recently being crystallized for human. In mammals and plants the COP9 complex consists of nine subunits, CSN 1–8 and CSNAP. The CSN regulates the activity of culling ring E3 ubiquitin and plays central roles in pleiotropy, cell cycle,...

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Publicado en:Genome Biol Evol
Main Authors: Barth, Emanuel, Hübler, Ron, Baniahmad, Aria, Marz, Manja
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860701/
https://ncbi.nlm.nih.gov/pubmed/27044515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evw073
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