Control of Multicellular Development by the Physically Interacting Deneddylases DEN1/DenA and COP9 Signalosome

Deneddylases remove the ubiquitin-like protein Nedd8 from modified proteins. An increased deneddylase activity has been associated with various human cancers. In contrast, we show here that a mutant strain of the model fungus Aspergillus nidulans deficient in two deneddylases is viable but can only...

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Autori principali: Christmann, Martin, Schmaler, Tilo, Gordon, Colin, Huang, Xiaohua, Bayram, Özgür, Schinke, Josua, Stumpf, Sina, Dubiel, Wolfgang, Braus, Gerhard H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567183/
https://ncbi.nlm.nih.gov/pubmed/23408908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003275
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