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Structural basis for non-canonical substrate recognition of cofilin/ADF proteins by LIM kinases

Cofilin/actin-depolymerizing factor (ADF) proteins are critical nodes that relay signals from protein kinase cascades to the actin cytoskeleton, in particular through site-specific phosphorylation at residue Ser3. This is important for regulation of the roles of cofilin in severing and stabilizing a...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Hamill, Stephanie, Lou, Hua Jane, Turk, Benjamin E., Boggon, Titus J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860616/
https://ncbi.nlm.nih.gov/pubmed/27153537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.04.001
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