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CRF receptor-1 antagonism mitigates Aβ pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease
INTRODUCTION: Stress and corticotropin-releasing factor (CRF) have been implicated as mechanistically involved in Alzheimer’s disease (AD), but agents that impact CRF signaling have not been carefully tested for therapeutic efficacy or long term safety in animal models. METHODS: To test whether anta...
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| 出版年: | Alzheimers Dement |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860182/ https://ncbi.nlm.nih.gov/pubmed/26555315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2015.09.007 |
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