Corticotropin-Releasing Factor Receptor-1 Antagonism Reduces Oxidative Damage in an Alzheimer’s Disease Transgenic Mouse Model

Reports from Alzheimer’s disease (AD) biomarker work have shown a strong link between oxidative stress and AD neuropathology. The nonenzymatic antioxidant, glutathione (GSH), plays a crucial role in defense against reactive oxygen species and maintenance of GSH redox homeostasis. In particular, our...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Alzheimers Dis
Prif Awduron: Zhang, Cheng, Kuo, Ching-Chang, Moghadam, Setareh H., Monte, Louise, Rice, Kenner C., Rissman, Robert A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486520/
https://ncbi.nlm.nih.gov/pubmed/25649650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-141722
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