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Origin and functional evolution of the Cdc48/p97/VCP AAA+ protein unfolding and remodeling machine
The AAA+ Cdc48 ATPase (alias p97 or VCP) is a key player in multiple ubiquitin-dependent cell signaling, degradation, and quality-control pathways. Central to these broad biological functions is the ability of Cdc48 to interact with a large number of adaptor proteins and to remodel macromolecular pr...
Enregistré dans:
| Publié dans: | J Mol Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860136/ https://ncbi.nlm.nih.gov/pubmed/26608813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.11.015 |
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