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“Bivalent” regions of cytosine methylation and H3K27 acetylation suggest an active role for DNA methylation at enhancers
The role of cytosine methylation in the structure and function of enhancers is not well understood. In this study, we investigate the role of DNA methylation at enhancers by comparing the epigenomes of the HCT116 cell line and its highly demethylated derivative, DKO1. Unlike promoters, a portion of...
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| Publié dans: | Mol Cell |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4859934/ https://ncbi.nlm.nih.gov/pubmed/27153539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.03.033 |
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