Heterogeneous patterns of DNA methylation-based field effects in histologically normal prostate tissue from cancer patients

Prostate cancer (PC) diagnosis is based on histological evaluation of prostate needle biopsies, which have high false negative rates. Here, we investigated if cancer-associated epigenetic field effects in histologically normal prostate tissue may be used to increase sensitivity for PC. We focused on...

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Publicat a:Sci Rep
Autors principals: Møller, Mia, Strand, Siri Hundtofte, Mundbjerg, Kamilla, Liang, Gangning, Gill, Inderbir, Haldrup, Christa, Borre, Michael, Høyer, Søren, Ørntoft, Torben Falck, Sørensen, Karina Dalsgaard
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233981/
https://ncbi.nlm.nih.gov/pubmed/28084441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40636
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