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Hypoxia-independent up-regulation of placental HIF-1α gene expression contributes to the pathogenesis of preeclampsia
Accumulation of hypoxia inducible factor-1α (HIF-1α) is commonly an acute and beneficial response to hypoxia, while chronically elevated HIF-1α is associated with multiple disease conditions including preeclampsia (PE), a serious hypertensive disease of pregnancy. However, the molecular basis underl...
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| 發表在: | Hypertension |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4859813/ https://ncbi.nlm.nih.gov/pubmed/25847948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05314 |
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