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Tissue transglutaminase contributes to the pathogenesis of preeclampsia and stabilizes placental angiotensin receptor AT1 by ubiquitination-preventing isopeptide modification

Preeclampsia is a life-threatening pregnancy disorder that is widely believed to be triggered by impaired placental development. However, the placenta-related pathogenic factors are not fully identified and their underlying mechanisms in disease development remain unclear. Here we report that the pr...

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Detalhes bibliográficos
Main Authors: Liu, Chen, Wang, Wei, Parchim, Nicholas, Irani, Roxanna A., Blackwell, Sean, Sibai, Baha, Jin, Jianping, Kellems, Rodney E., Xia, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052572/
https://ncbi.nlm.nih.gov/pubmed/24191290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02361
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