Elevated Transglutaminase Activity Triggers Angiotensin Receptor Activating Autoantibody Production and Pathophysiology of Preeclampsia

BACKGROUND: Preeclampsia (PE) is a life‐threatening hypertensive disorder of pregnancy associated with autoantibodies, termed AT (1)‐AA, that activate the AT (1) angiotensin receptor. Although the pathogenic nature of these autoantibodies has been extensively studied, little is known about the molec...

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Dettagli Bibliografici
Pubblicato in:J Am Heart Assoc
Autori principali: Liu, Chen, Luo, Renna, Elliott, Serra E., Wang, Wei, Parchim, Nicholas F., Iriyama, Takayuki, Daugherty, Patrick S., Blackwell, Sean C., Sibai, Baha M., Kellems, Rodney E., Xia, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845265/
https://ncbi.nlm.nih.gov/pubmed/26675250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002323
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