Elevated Transglutaminase Activity Triggers Angiotensin Receptor Activating Autoantibody Production and Pathophysiology of Preeclampsia

BACKGROUND: Preeclampsia (PE) is a life‐threatening hypertensive disorder of pregnancy associated with autoantibodies, termed AT (1)‐AA, that activate the AT (1) angiotensin receptor. Although the pathogenic nature of these autoantibodies has been extensively studied, little is known about the molec...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Liu, Chen, Luo, Renna, Elliott, Serra E., Wang, Wei, Parchim, Nicholas F., Iriyama, Takayuki, Daugherty, Patrick S., Blackwell, Sean C., Sibai, Baha M., Kellems, Rodney E., Xia, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845265/
https://ncbi.nlm.nih.gov/pubmed/26675250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002323
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